Apoptosis and Development

An involved paper on genetics. The author delves into the scientific language of cell migration and organism development.

This is a deep paper on genetics. The author delves into the scientific language of cell migration and organism development. Although apoptosis is an important mechanism in the development and homeostasis of many organisms, little is known about the mechanisms underlying apoptosis. Investigation into apoptotic genetics has yielded promising results, yet more research needs to be undertaken. This research may eventually yield insights into treatment of diseases linked to apoptosis, such as cancer and AIDS.
“A developing organism undergoes many dramatic changes, including cell migration, proliferation and cell death. Apoptosis, a form of cell death, is characterised by nuclear condensation, plasma membrane alterations and the lack of an inflammatory response. Apoptosis is the fate of many cells in development and is necessary for normal development in a large number of organisms. The genes ced-3 and ced-4 regulate initiation of apoptosis in C. elegans. The mammalian homolog of ced-3, once thought to be Interleukin-1-Beta converting enzyme (ICE), is still under investigation. In C. elegans, ced-9 regulates genetic inhibition, while bcl-2 does the same in mammals.”